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ACRP ACRP-CP Exam Questions

ACRP ACRP-CP Exam Questions Answers

ACRP Certified Professional Exam

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ACRP ACRP-CP Sample Questions – Free Practice Test & Real Exam Prep

Question #1

A monitor identifies multiple deviations from a protocol-defined timeline for studyprocedures. The monitor is unable to identify proof of PI review and assessment of thedeviations. The monitor discusses the deviations with the PI, who initiates a CAPA. What isthe purpose of this CAPA?

  • A. To determine if a protocol amendment is needed  
  • B. To escalate corrective actions to the regulatory authority  
  • C. To determine if the deviations invalidate the data  
  • D. To establish a procedure for PI oversight of protocol deviations  
Answer: D 
Question #2

In order to conduct open-label, parallel group clinical trials according to sound scientificprinciples, which of the following design elements should be included?

  • A. Randomization  
  • B. Privacy controls  
  • C. Blinding  
  • D. Placebo-controlled  
Answer: A 
Question #3

Who is responsible for submitting a protocol amendment to the IRB/IEC? 

  • A. Sponsor  
  • B. CRC  
  • C. Investigator  
  • D. CRA  
Answer: C 
Question #4

Which statement does NOT represent a study monitor's responsibilities? 

  • A. Check the accuracy and completeness of case report forms with source documents.  
  • B. Provide communication between the sponsor and the PI.  
  • C. Report serious adverse events to the IRB/IEC.  
  • D. Verify that the PI has adequate qualifications and resources to conduct the study.  
Answer: C 
Question #5

An investigator participating in a multicenter clinical trial has had 2 of the 4 subjectsadmitted to the emergency room for life-threatening infections. The investigator made thedecision to stop treatment with IP and test for infections in the remaining subjects. Whatare the NEXT steps the investigator should take?

  • A. Add the risk of infection to the ICF and submit to the IRB/IEC for review.  
  • B. Update the IB to add the risk of infection and submit to the sponsor for approval.  
  • C. Notify the sponsor of the change in study plan and submit the deviation to the IRB/IECfor review.
  • D. Discontinue current subjects from the study and monitor subjects for any anticipatedsafety events. 
Answer: C 
Question #6

SAEs must be reported immediately by the site to the: 

  • A. Sponsor.  
  • B. Regulatory agency.  
  • C. IRB/IEC.  
  • D. DSMB/IDMC.  
Answer: A 
Question #7

Who determines what criteria and procedures should be followed if a subjectdiscontinues/withdraws their consent?

  • A. CRO  
  • B. Subject  
  • C. PI  
  • D. Sponsor  
Answer: D 
Question #8

While consenting a potential subject, a coordinator discovered the subject could not read.Under what conditions can this potential subject be enrolled?

  • A. Locate a translator and have them work with the person.  
  • B. Get an impartial witness involved in consenting this person.  
  • C. Have the Principal Investigator consent the person.  
  • D. There are no circumstances under which this person can be enrolled.  
Answer: B 
Question #9

Who determines the age of assent for pediatric studies? 

  • A. PI  
  • B. Parent  
  • C. Sponsor  
  • D. IRB/IEC  
Answer: D 
Question #10

A hospital site is being considered for a trial that requires the IP refrigerator to becontinuously monitored using the sponsor-provided Wi-Fi-enabled thermometer. Thehospital’s Wi-Fi connectivity is inconsistent. During site selection, how should the CRAproceed?

  • A. Accept this site and plan to undertake routine safety evaluations of the IP.  
  • B. Accept this site and implement and maintain QA and QC systems with written SOPs.  
  • C. Before accepting this site, report the risk to the trial sponsor and await their decision.  
  • D. Before accepting this site, ensure the refrigerator is calibrated and functioning properly.  
Answer: C 
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